GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs7267979 | 1 | rs4815417 | chr20:25379526 | ENTPD6 | chr20:25176339-25207360:+ | 0.32 | 7.36 | 8.31E-13 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815417 | chr20:25379526 | FAM182A | chr20:26035250-26067552:+ | 0.19 | 3.46 | 0.000595 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815417 | chr20:25379526 | FAM182B | chr20:25744102-25848786:- | -0.26 | -5.36 | 1.29E-7 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815417 | chr20:25379526 | NINL | chr20:25433338-25566153:- | 0.35 | 7.19 | 2.44E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815417 | chr20:25379526 | PYGB | chr20:25228706-25278647:+ | 0.15 | 3.73 | 0.000218 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815418 | chr20:25382211 | ENTPD6 | chr20:25176339-25207360:+ | 0.32 | 7.24 | 1.85E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815418 | chr20:25382211 | FAM182A | chr20:26035250-26067552:+ | 0.19 | 3.48 | 0.000546 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815418 | chr20:25382211 | FAM182B | chr20:25744102-25848786:- | -0.26 | -5.4 | 1.05E-7 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815418 | chr20:25382211 | NINL | chr20:25433338-25566153:- | 0.33 | 6.9 | 1.67E-11 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815418 | chr20:25382211 | PYGB | chr20:25228706-25278647:+ | 0.16 | 4.03 | 6.53E-5 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815420 | chr20:25383979 | ENTPD6 | chr20:25176339-25207360:+ | 0.32 | 7.22 | 2.08E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815420 | chr20:25383979 | FAM182B | chr20:25744102-25848786:- | -0.26 | -5.55 | 4.67E-8 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815420 | chr20:25383979 | NINL | chr20:25433338-25566153:- | 0.34 | 6.91 | 1.53E-11 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815420 | chr20:25383979 | PYGB | chr20:25228706-25278647:+ | 0.16 | 4 | 7.34E-5 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815421 | chr20:25386509 | ENTPD6 | chr20:25176339-25207360:+ | 0.32 | 7.24 | 1.85E-12 | Liver enzyme levels (alkaline phosphatase) |